
In one fell swoop today, Sen. David Vitter (R-LA) revived the specter of health care death panels, and called into question the FDA's ability to judge the effectiveness of breast cancer medication.
According to the Associated Press, Vitter slammed the FDA, which voted 12-1 to drop its endorsement of the breast cancer drug Avastin after research showed that its additional positive effects were minimal, but it was associated with increased liver toxicity. Vitter called the decision "sickening" -- but not because the FDA's accelerated approval of the drug in 2007 went against the medical advise of its advisory committee or because women with metastatic breast cancer using the drug were more likely to die. Instead, he compared the FDA's reversal to withholding care for patients whose lives are "not deemed valuable enough."
This puts Vitter into the same camp as noted pharmaceutical expert Andrew Breitbart, whose website Big Government today lambasted the FDA for "rationing."
"As tragic as it is for breast cancer patients today, this arbitrary shift is a preview of one of the tools in the government health care rationing toolbox," reads a column on Breitbart's site.
"The government is not just saying outright that they won't cover the cost of this, they are hiding their financial decisions behind language like "clinically meaningful" to lead people to believe the drug doesn't work," the article continues. "The Avantis [sic] case is setting the precedent for the government to arbitrarily deny coverage to millions of American's based on cost alone."
Meanwhile, the Boston Globe quotes a specialist familiar with Avastin's development saying that the ruling has limited implications. "What the FDA would be saying is ... for women with breast cancer, Avastin with paclitaxel was not better than paclitaxel alone. It doesn't mean the drug wouldn't work for other types of breast cancer or with other types of chemotherapy. Or for other types of cancer," said Dr. Mark Kieran, who studies vascular biology in the same lab as Dr. Judah Folkman, who, according to the Globe, advanced the theories that led to Avastin's creation.

Barack ObamaJob Approval |
45.2%Approve | 49.7%Disapprove | -4.5Spread |
CongressionalGeneric Ballot |
41.7%DEM | 47.4%GOP | +5.7SpreadR |
TPM Stories Now Surging on Digg.com

ericf
July 28, 2010 1:33 PM
Let me guess, Vitter and Breitbart get money from the maker of Avastin? Is the company connected to Republicans?
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
marcomay
July 28, 2010 2:27 PM in reply to ericf
David Vitter, who frequented with prostitutes and is still in office...Andrew Breitbart, a pathological liar who should be in prison...two upstanding, patriotic Americans. Can it get any more sickening? When will the Democrats go on the attack against scumbags like these two???
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Zentrails
July 29, 2010 10:14 AM in reply to marcomay
You forgot Fox news.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
KingCool
July 28, 2010 1:33 PM
Vitter's a royal douche. 'nuff said.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
traitorjoe
July 28, 2010 3:28 PM in reply to KingCool
Vitter's still upset the FDA didn't warn him about the dangers of adult diapers and hooker sex. Those rashes will haunt him forever.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Signalman
July 28, 2010 5:13 PM in reply to traitorjoe
FTW
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
jsdc007
July 28, 2010 4:06 PM in reply to KingCool
And a douche is actually a medical device. I say regulate this wretch and the turd he associates with (Breitbart), and take them both off the markeet.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
nova voter
July 28, 2010 1:34 PM
"noted pharmaceutical expert Andrew Breitbart"
holy crap, the judges just gave this line 10.0's across the board. brian, you are the mary lou of snark.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
glblank
July 28, 2010 1:42 PM in reply to nova voter
maybe he's a Richard Pryor kind of expert. With any luck we'll see he go up in the next meth lab fail.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
CityGuy
July 28, 2010 2:03 PM in reply to nova voter
Co-sign. Priceless.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
zonk
July 28, 2010 2:29 PM in reply to nova voter
Heh...
I guess sounding like you're constantly addled on drugs CAN make you a noted expert!
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Walter Mitty
July 28, 2010 1:40 PM
Shorter Vitter - "See look I'm caring about women issues - everybody paying attention? I'm here caring about woman issues!"
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
midnight rambler
July 28, 2010 1:52 PM in reply to Walter Mitty
"...by promoting toxic, ineffective drugs for women."
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
hunter
July 28, 2010 1:55 PM in reply to Walter Mitty
s/caring/clueless/g
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Sniffit
July 28, 2010 1:41 PM
Captain Pampers strikes again.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
FlownOver
July 28, 2010 4:45 PM in reply to Sniffit
Really.
I have to suppress a laugh whenever I see a headline that has the words "Vitter" and "smear."
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
July 29, 2010 10:35 AM in reply to FlownOver
Ouch!
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
septictank
July 28, 2010 1:45 PM
Well, all pharmas are connected to the GOP, but I don't think Genentech is one of the more ideologically Republican companies -- they're supposed to be the Apple of the industry. Wouldn't be surprised if one of their gazillion lobbyists or flacks showed Vitter and Breitbart some love, tho
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
sickofyoujerks
July 28, 2010 1:52 PM
Follow the money, this douche doesn't open his yap unless he's getting paid, guaranteed
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
sickofyoujerks
July 28, 2010 1:55 PM
Can someone explain the whole diaper thing? Does he fill it before, during, or afterwards? Then what, does he play in it?
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Sniffit
July 28, 2010 2:06 PM in reply to sickofyoujerks
I'm willing to bet he has trouble "filling" it EVER, if you catch my meaning. Dude never graduated to Pull-Ups.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Mrwilson1
July 28, 2010 2:01 PM
so for some reason it is better to give a person medicine that will give them a problem with her liver toxicity and that women who have breast cancer problems are more likely to die on it, then it is to withhold the medicine.
I suppose to the newly crowned tea party member that would make sense
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
ohyeathatsright
July 28, 2010 2:02 PM
While we're at it, let's bring back Phen-Phen!
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
PartTimeRoadie
July 28, 2010 2:59 PM in reply to ohyeathatsright
Gah, beat me too it.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
ohyeathatsright
July 28, 2010 5:51 PM in reply to PartTimeRoadie
I just don't want panels killing anyone, let's leave that to the drugs. If enough people die from taking it, then the free market will take care of itself!
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Whenwillthisnightmareend
July 28, 2010 2:03 PM
It's obvious who's paying Vitter', and Breitbart's package of perks, Big Pharma! They want the US government to preserve their unfettered right to bamboozle and defraud the people of this nation by pawning off snake oil with no proof of effectiveness, and in spite evidence of harm. These people have no credibility with informed voters; only problem is the desire, or lack thereof, of certain segments of the nation. If diaper sex with prostitutes and blatant lying intended to stoke the fires of racism doesn't make a difference, then sadly, nothing will.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
ADad
July 28, 2010 2:21 PM
What is going in LA that allows Diaper David to be competitive for re-election? Why does he have even a shred of credibility? Any LA-folks with insights to share?
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
July 28, 2010 2:28 PM in reply to ADad
Not from LA, but I'm betting it's the -(R) after his name along with him being a white Christian. It's pretty clear that that's all they care about.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Seafarer
July 28, 2010 2:27 PM
Will TPM be looking into contributions from Genentech or Roche Group, or their executives? Those firms appear to be the main interests behind Avastin.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
calbearinillinois
July 28, 2010 8:38 PM in reply to Seafarer
Roche (the parent) is a Swiss concern that doesn't do much directly with the US. Most of their subsidiaries (and I've done work with the legal staff of a couple, and know a few more through that work) tend to work through organizations like PhRMA and BIO rather than doing a lot of direct lobbying. Typically, while the industry can be nasty in terms of sales fights and lawsuits with each other, they align pretty well on big picture issues like patent laws, FDA approvals, Medicare/Medicaid reimbursement, etc.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
stevez314159
July 28, 2010 2:38 PM
Vitter and Breitbart don't even know how to spell FDA.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Snig
July 28, 2010 2:40 PM
Sounds like they've never read about how drugs get approved. Vast majority of experimental meds wash out before becoming accepted. More short term self-interest and anti-intellectualism from the party that denies global warming.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
MrRandom
July 28, 2010 2:43 PM
Ladies have no fear the diaper dandy has your interests at heart.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
John M
July 28, 2010 2:43 PM
"As tragic as it is for breast cancer patients today, this arbitrary shift is a preview of one of the tools in the government health care rationing toolbox," reads a column on Breitbart's site.
----------------------------------------------------
Breitbart fails to mention that the United States has had massive rationing for decades, and the death panel doing the massive rationing is made up of the insurance company bureaucrats who decide who gets treatmant and what treatment they get, so it's the insurance company bureaucrats, not physicians, who make the medical decisions for American patients.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
July 28, 2010 3:05 PM in reply to John M
SHHHHH! You shut your mouth with your facts and logic. It matters not that insurance companies have these "death panels," as you liberals call them, because that's private industry and they can do whatever they want. If you don't like it, vote with your wallet! The Socialist Party will set-up a single panel of death experts to preside over every single person's medical decisions; it's in the bill on page 666 section 6 subsection 6 part 6, read it for yourself!
:)~
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
July 29, 2010 10:58 AM in reply to Kyle
I get jokes.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Blueline99
July 28, 2010 5:10 PM in reply to John M
The real story behind this is how Pharmaceutical companies "re-invent" their drugs in an attempt to side step patent limitations.
They are just being called out on the fact that this "new" drug doesn't help. I love how Vitter and Breitbart back their claims with the preponderance of evidence that shows this drug has any positive effect at all.
They prefer to use scary words to frighten their people int a lathering mob.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Wes
July 28, 2010 3:02 PM
What the heck do these jerks know about pharmacology? Avastin was "fast-tracked" by the FDA, which means is they don't actually do a full assessment of effectiveness and safety because the people intended to use it have terminal disease (metastatic cancer), so they want to get the drug to these people as quickly as possible. Fast-tracked drugs frequently are shown later to not be very effective or do more harm than good.
Why Breitbart/Vitter seized this particular case to go all death-panely is beyond me. I guess they think it'll score them some points in the election, but last time I checked people are more worried about the economy and jobs than fictional death panels.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
PAvoter
July 28, 2010 3:12 PM
I think I will wait until Sarah Palin and Faux News weighs in on this compelling issue.
But if FDA advisory panels fit into the category of government regulations, then when the Republicans take control, all those will be eliminated. Then we will all be safe.
But the Vitter link is probably through Billy Tauzin. Billy Tauzin, the backslapping former Louisiana congressman who went on to earn $2 million a year as head of the drug industry's powerful Washington trade group, PhRMA, is stepping down from his post in June 2010.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
septictank
July 28, 2010 4:02 PM
If I were Melancon, I'd be out there hammering him with a message of "Vitter wants to waste billions on a drug that doesn't do shit for breast cancer patients -- all to help his drug company buddies. And people wonder why we've got deficits up the wazoo?"
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
slb
July 28, 2010 6:36 PM
I'm sorry to do this, but:
...but not because the FDA's accelerated approval of the drug in 2007 went against the medical advise of its advisory committee...
"advice," not "advise." Advise (əd-vīz) is a verb. Advice (əd-vīs) is a noun. When you advise someone, what you give them is advice.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
xargaw
July 28, 2010 7:15 PM
Specific candidates aside, the problem with the FDA is that Big Pharma now controls drug testing, manipulates results and profits trump safety. Evidence of this is the substantial increase in side effects of drugs AFTER they are marketed over the clinical testing stats. Independent drug testing without corporate influence is long gone and the patient is more often than not the victum of this greed. Granted, Vitter is a real intellectual lightweight and creep, but he also refuses to, or has no understanding of how the FDA works. The failure of the FDA is not government control, but corporate control of a government agency.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
Quitty
July 28, 2010 8:07 PM
As tragic as it is for breast cancer patients today, this arbitrary shift is a preview of one of the tools in the government health care rationing toolbox
By this standard, any government regulation of the pharmaceutical industry could be called "rationing."
As someone who's had a 20-year career marketing medical devices, on and off for big pharma companies, I can personally attest to big pharma's objectives in launching new drugs: Get them to market as fast as possible and make boatloads of money before the FDA pulls them off the market and/or the lawsuits begin to hit. They know how dangerous many of these drugs are long before they bring them to market. They still make way more money than they ever end up paying out in settlements. It's their business model.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
calbearinillinois
July 28, 2010 8:24 PM
The FDA spent most of the last 10 years as the lapdogs of Big Pharma, often overruling its own scientific panels in favor of corporate lobbying. They even supported a move by the corporations to create a safe harbor from lawsuits as long as they drug was used in keeping with FDA approval - Supreme Court shot it down, but it was close. Now, they actually pull a recommendation so they are in line with science - not economics, because this decision has little to no cost to the Federal government - and Vitter gets mad? And he claims it is somehow rationing, even though the FDA doesn't write, fill or pay for any prescriptions? Gag and double gag.
This drug still has FDA approval. It still has a number of uses. Doctors will prescribe it, insurance companies will cover it, and patients will get it - just not as often, or in situations where it has no efficacy. Not rationing, but certainly rational. Maybe that's Vitter/Breitbart's hangup.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
calbearinillinois
July 28, 2010 8:27 PM
Shorter Vitter - Who needs the FDA? You should have the absolute freedom to buy quacky patent medicines and die horribly from the complications. So long as you can't sue the company for selling it to you, seeing as how it was your free choice and all.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
chitowner
July 29, 2010 3:35 AM
Ah, the hateful ho' hopper tells another twisted lie.
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?
July 29, 2010 4:58 PM
Oh, Breitbart's an "expert": I assume he's an "expert" in the same way that he's an "expert" on Shirley Sherrod's career. I see.
Emily
http://emilyscoffeespot.blogspot.com
Reply | Flag Abuse
Are you sure this comment violates TPM's Terms of Service?